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 cell complex cytokine death disease domain enzyme immune immunology inflammasome inflammation kinase macromolecule mitotic molecules nek7 neurodegenerative nrlp3 polypeptide proinflammatory protein pyroptosis system

The Mitotic Kinase NEK7 Binds To Inactive NRLP3 Leading To The Assembly And Activation Of The NLRP3 Inflammasome Stock Image


The mitotic kinase NEK7 binds to inactive NRLP3 leading to the assembly and activation of the NLRP3 inflammasome Stock Photo
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The mitotic kinase NEK7 binds to inactive NRLP3 leading to the assembly and activation of the NLRP3 inflammasome #181178707
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From left to right: apo-NEK7 inactive, active NEK7, NE7 bound to NLRP3. .Inflammasomes elicit host defense inside cells by activating caspase-1 for cytokine maturation and cell death. Dysregulation of inflammation activation can lead to cancer, autoimmune and neurodegenerative diseases. Source: PDB entries 2WQM, 6NPY

The mitotic kinase NEK7 binds to inactive NRLP3 leading to the assembly and activation of the NLRP3 inflammasome, illustration
The mitotic kinase NEK7 in the inactive left and active forms
G2-mitotic-specific cyclin B1, cyclin-dependent kinase 1 and cyclin-dependent kinase regulatory subunit 2 with Flavopiridol
Microtubule Affinity Regulating Kinase (MARK) Mitotic
Microtubule Affinity Regulating Kinase (MARK) Mitotic spindle s