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The Mitotic Kinase NEK7 Binds To Inactive NRLP3 Leading To The Assembly And Activation Of The NLRP3 Inflammasome Stock Image


The mitotic kinase NEK7 binds to inactive NRLP3 leading to the assembly and activation of the NLRP3 inflammasome Stock Photo
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The mitotic kinase NEK7 binds to inactive NRLP3 leading to the assembly and activation of the NLRP3 inflammasome #181178707
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From left to right: apo-NEK7 inactive, active NEK7, NE7 bound to NLRP3. .Inflammasomes elicit host defense inside cells by activating caspase-1 for cytokine maturation and cell death. Dysregulation of inflammation activation can lead to cancer, autoimmune and neurodegenerative diseases. Source: PDB entries 2WQM, 6NPY