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Title
Cryo-EM structure of human T-cell leukemia virus type-1 HTLV-1 intasome #209766007
Description
Integration of the reverse-transcribed viral DNA into host chromosomes is a critical step in the life-cycle of retroviruses, including an oncogenic deltaô-retrovirus human T-cell leukemia virus type-1 HTLV-1. Retroviral integrase forms a higher order nucleoprotein assembly intasome to catalyze the integration reaction. Animated 3D cartoon simulation in three projections, black background.