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Title
Activation of the melanocortin receptor by an anti-obesity drug #217998900
Description
The melanocortin receptor 4 is crucial for appetite, energy homeostasis and body-weight control in the central nervous system. Binding of the agonist setmelatonide to the melacortin receptor leads to a G-protein coupled C-AMP signaling pathway. Source: PDB entries 7aue, 6r3q,. Israeli, H. et al. 2021 Science