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Structure Of Proliferating Cell Nuclear Antigen (PCNA) Bound To A Small Molecule Inhibitor Stock Photography


Structure of Proliferating Cell Nuclear Antigen (PCNA) bound to a small molecule inhibitor Stock Photo
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Structure of Proliferating Cell Nuclear Antigen (PCNA) bound to a small molecule inhibitor #225618446
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Proliferating cell nuclear antigen PCNA is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication. PCNA is a homotrimer and achieves its processivity by encircling the DNA, where it acts as a scaffold to recruit proteins involved in DNA replication, DNA repair, chromatin remodeling and epigenetics. 3D cartoon and Gaussian surface models, chain instance color scheme, based on PDB 3wgw, white background.