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Title
Chimeric antigen receptor CAR therapy: Engineered natural killer cell attacks a cancer cell #253411352
Description
Engineered receptors light blue on the surface of a natural killer cell NK white bind specifically to PD-L1 molecules red on a cancer cell cell. This activates a signal cascade in the NK-cell leading to the segregation of vesicles that contain perforin and granzyme. The perforins build channels for the granzymes which enter the leukemia cell and activate finally the apoptosis cell death