Human Pancreas. Type 2 Diabetes Mellitus Stock Photo

Human pancreas. Islet of Langerhans with a drastic reduction of endocrine cells and pink hyalinization (with deposition of amyloid). These deposits have resulted in the death of the beta cells, which are responsible for releasing insulin. This change is common in the islets of patients with type II diabetes mellitus. This amyloid contains protein derivatives of amylin, or islet amyloid polypeptide